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Diazepam 10 mg for sleep
Off-label uses mean that FDA has not approved to use of the drug for this intention or for this way of use, it approved it for other uses, other dosage forms, age group, or other doses.
Using the drug for off-label intentions is entirely legal and very common.
One out of five patients in the U.S. is using drugs for off-label uses.
Examples of off-label uses:
- When chemotherapy is approved for a specific type of cancer, and the doctor uses it for another type
- When the capsule form is approved for use, and the doctor uses the oral solution
- When the drug is approved to be taken once a day, but the doctor sees that two tablets are the correct dose.
Diazepam 10 mg for sleep is an off-label use.
Insomnia is a very common sleeping problem.
- In 2005, A poll in America found that 35% of adults suffer from Insomnia every night
- In 2007, The National Sleep Foundation in America found that 67% of women are experiencing sleeping problems.
Diazepam 10 mg for sleep has other FDA approved uses :
- Anxiety
- Alcohol withdrawal symptoms
- Seizures
- Relaxation of muscle spasms
- Sedation before medical procedures
Diazepam 10 mg for sleep is a benzodiazepine drug that belongs to CNS (Central Nervous System) depressants.
It acts by enhancing the effects of a neurotransmitter called GABA (Gama Amino-butyric acid), which decreases the excessive activity of the brain.
Before using the drug, you have to be aware of the following.
Allergies:
Patients, who have allergies to food, dyes, preservatives, animals, and drugs, must carefully, tell their health care provider about them, and the list of ingredients of the drug must be carefully read.
Pediatrics:
Safety and efficacy have been established in children older than 6 months old, under this age, diazepam for sleep should not be used as efficacy and safety are not established.
Geriatrics:
There are no specific problems with the use of diazepam with geriatrics, but drowsiness, dizziness, confusion, clumsiness, and unsteadiness may occur.
Age-related kidney problems can also happen; caution and monitoring must be taken into consideration when used in geriatrics.
Breastfeeding:
The use of diazepam 10 mg for sleep in breastfeeding women has proved to cause harmful infant effects.
An alternative drug or alternative feeding options should be considered.
Before using diazepam 10 mg for sleep, you have to tell your doctor if you are suffering from the following medical conditions:
- Alcohol or drug abuse or dependence or a history of them
- Depression or a history of it
- Breathing problems like respiratory depression
- Mental health problems or a history of them
- Seizures, diazepam 10 mg for sleep may worsen them
- Narrow-angle Glaucoma
- Severe liver problems
- Kidney problems
- Myasthenia gravis (a condition causing the muscles to be weak and tired)
- Sleep apnea (a condition causing temporary stop of breathing during sleep)
- Diazepam 10 mg for sleep may be used in mild and moderate liver problems but with caution
Drug-drug interactions:
If you are taking other drugs, you must tell your doctor about them, as they may cause serious interactions if used with diazepam 10 g for sleep.
Drugs causing serious interactions to use an alternative drug:
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
- nefazodone
- rifabutin
- rifampin
- selinexor
- sodium oxybate
- St John’s Wort
- sufentanil SL
- tipranavir
- tucatinib
- valerian
- voxelotor
Other drugs must be used with close monitoring if used with diazepam:
- alprazolam
- amitriptyline
- azelastine
- baclofen
- belladonna and opium
- bosentan
- butabarbital
- carbamazepine
- chloral hydrate
- chlorpheniramine
- dantrolene
- dexamethasone
- estazolam
- fluconazole
- fluoxetine
- gabapentin
- hydrocortisone
- hydromorphone
- imipramine
- itraconazole
- ketamine
And others take care of any combinations of drugs.
Not just drugs, alcohol, and grapefruit may increase the risk of certain side effects, don’t use them in combination with diazepam 10 mg for sleep.
Side effects:
Diazepam 10 mg for sleep may cause several side effects.
Common side effects (1-10%)
- Ataxia (difficulty in control of muscles and coordination)
- Euphoria (intense excitement and happiness)
- Incoordination
- Somnolence (sleepiness)
- Rash
- Diarrhea
Common side effects (frequency not known)
- Hypotension
- Fatigue
- Muscle weakness
- Respiratory depression
- Urinary retention
- Depression
- Incontinence (inability to control urination or defecation)
- Blurred vision
- Dysarthria (speech muscles are damaged)
- Headache
- Skin rash
- Changes in salivation
Serious side effects that need immediate medical attention
- Neutropenia (very few numbers of neutrophils, a type of white blood cells, that are used to fight infections)
- Jaundice (kidney problem causing yellow skin and eyes)
- Pain
- Swelling
- Thrombophlebitis (inflammation causes a blood clot that blocks a vein or more especially in the legs)
- Carpal tunnel syndrome (a common medical condition causing pain, numbness, or tingling in hands and arms)
- Tissue necrosis (death of the tissue)
- Phlebitis (inflammation of the vein) if the IV administration was rapid
If you suffer from a severe sleeping problem, talk to your doctor about diazepam 10 mg for sleep, and how suitable is it for your condition.