Diazepam 10 mg UK is a derivative of the benzodiazepines family, it has anxiolytic, hypnotic, and anticonvulsant properties.
Diazepam works by potentiating the inhibitory effects of GABA (gamma-aminobutyric acid), a certain transmitter in the brain.
It is a controlled substance that should not be used except under the supervision of a doctor, and should not be shared with others.
Uses and indications:
It is also prescribed for children in,
The nasal spray form of diazepam is indicated in patients 6 years old and older patients in the treatment of seizure activity different from the usual pattern of seizure in these patients.
Dosage and administration:
In adults, diazepam 10 mg UK is used by the following doses,
The treatment of anxiety states:
2 – 10 mg every 6 – 12 hours
No more than 30 mg every 8 hours
In the treatment of alcohol withdrawal symptoms:
10 mg every 6 – 8 hours during the first 24 hours, then the dose is reduced to 5 mg every 6 – 8 hours
As adjunctive therapy in the management of muscles spasms:
2 – 10 mg every 6 – 12 hours
Dose modifications:
In patients with renal impairment: The dose doesn’t need to be adjusted except if it is going to be used for a long time.
In patients with hepatic impairment: The maintenance dose is decreased by 50%
Interactions:
Diazepam 10 mg UK may seriously interact if used with different substances.
Drug-drug interactions:
Diazepam 10 mg UK seriously interacts with the following drugs and alternatives should be used.
Drug-food interactions:
Diazepam 10 mg UK interacts with grapefruit and grapefruit juice leading to serious side effects.
Don’t change the amounts of grapefruit taken in your diet before talking with your doctor.
Drug-alcohol interactions:
Diazepam 10 mg UK taking with alcohol increases the sedative effects of alcohol, including drowsiness, dizziness, and tiredness.
Drug-weight interactions:
Obesity increases the distribution of the drug in fats which may lead to increased risks of toxicity.
Diazepam 10 mg UK should be used carefully in obese patients to avoid toxicity.
That’s why, the loading doses are determined based on actual body weight, while maintenance doses are determined on ideal body weight to avoid toxicity.
Drug-disease interactions:
If you suffer from the following diseases, you should not use diazepam 10 mg UK.
Adverse effects:
Diazepam 10 mg UK adverse effects differentiate into adverse effects that require immediate medical attention and those that don’t.
Adverse effects require immediate medical attention:
More common
Incidence not known
Adverse effects don’t require immediate medical attention:
Incidence not known
Black box warning:
Using diazepam 10 mg UK with opioid medications may be extremely dangerous, causing profound sedation, respiratory depression, coma, and even death.
Diazepam 10 mg UK is a very effective medication that is used in the treatment and management of many disorders.
If you think you suffer from any of the above conditions, discuss with your health care provider if diazepam is suitable for you.
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