Valium UK

Valium UK is a benzodiazepine drug, which contains diazepam as an active constituent.

Valium UK has FDA approved in the treatment of anxiety, seizures, muscle spasm, alcohol withdrawal symptoms, and sedation before medical procedures. there is an off-label use of diazepam (non-FDA approved), like sedation in ICU and treatment of spasticity in children with cerebral palsy.

Off-label, use means: the use of certain medication in treating conditions other than that is usually used (FDA approved).

Example of off label use:

• Medication used to treat the condition that is not FDA approved.
• Use different doses other than the approved dose.
• Use medication in children while only approved on adults.

Valium UK adverse effects:

• Blurred vision.
• Muscle weakness.
• Difficulty in urination.
• Trouble in speaking.
• Allergic reaction.
• Leukopenia (decreased in white blood cells count).
• Memory loss.
• Ataxia: a condition characterized by difficulty in coordination, balance, and speech. So that affecting your balance, walking and talking.
• Impaired motor ability.
• Dysarthria: neurological injury caused by speech disorder.
• Hypotension, syncope.
• Respiratory depression.
• Apnea: sudden stop of breathing.
• Dry mouth.
• Increased appetite.
• Elevation of liver function test.

Contraindications of using Valium UK:

Valium UK is contraindicated in patients suffering from the following conditions:

• Allergy to benzodiazepine.
• Myasthenia gravis: a condition considers an autoimmune disease affecting skeletal muscles that lead to muscle weakness.
• Severe hepatic insufficiency.
• Sleep apnea: known as obstructive sleep apnea caused mainly in obese patients, the airway was blocked cause suddenly stop breathing.
• Planning to be pregnant.
• Respiratory depression.
• Children under 6 months of age.
• Acute narrow-angle glaucoma.
• Chronic psychosis.

Special population:

• Pediatric: Valium UK is contraindicated in pediatric under 6 months of age.
• Elderly: valium should be used with caution in elderly patients as extended effects occur due to a decrease in its clearance. So should start with a low dose and increased gradually if the patient tolerates it.
• Pregnancy: it considered a contraindication to use valium in pregnant women or women planning for pregnancy. Reported congenital malformation and developmental abnormalities were associated with using valium.
• Breastfeeding: valium can be secreted in breast milk so have adverse effects on infants.
• Obese: effect of valium extended in obese patients.
• Psychotic: not recommended to use valium in psychotic patients.

Drug-drug interactions between valium and other medications:

Many medications should be avoided during the use of Valium:

 

• Fusidic acid(systemic).
• Olanzapine
• Oxybate salt products.

Medications that decrease the effect of Valium:

• Theophylline derivatives.

Medications that increase the effect of Valium and may increase risk of toxicity:

 

• Kava kava.
• Magnesium sulfate.

Your doctor may advise you to monitor certain parameters to ensure safety like:

• Heart rate.
• Respiratory rate.
• Blood pressure.
• Liver enzymes.
• CBC (complete blood count).
• Mental status.

Besides the monitoring of your vital signs, you should be careful in doing the following:

• do not drive or operate machinery.
• Do not use Valium for a long duration without referring it to your doctor.
• Do not stop taking Valium suddenly.
• Be careful if you are drinking alcohol.

Valium overdose, what are symptoms, and how it is treated?

Overdose means too excessive a dose that may be toxic, that happened by accidentally take more quantity or amount of your medication.

Sometimes happen when there were drug-drug interactions increase the level of your medication in your body.

Valium as other medication may take by overdose.

Symptoms of valium overdose:

 

• Muscle weakness.
• Brady cardia.
• Respiratory depression.
• Blurred vision.
• Low blood pressure.
• Lips and nails turning blue.
• Upset stomach.

How to manage valium overdose?

Management of valium overdose:

• Activated charcoal.
• Maintain a clear airway.
• Closely monitor overdose symptoms.
• Management of hypotension.
• Monitor level of consciousness.

Is there an antidote for Valium?

Antidote means a drug that counteracts act effect of another drug.

Mainly used in case of treating certain drug overdose.

Examples of an antidote:

• Acetylcysteine for acetaminophen overdose.
• Activated charcoal for many oral poisonings.
• Atropine for organophosphorus products.
• Digoxin immune fab for digoxin toxicity.

In case of Valium overdose, Flumazenil is an antidote used for the management of Valium toxicity.

What happened when you use Valium for a long time?

The use of Valium for a long time may increase your risks for abuse, misuse, and addiction.

Abuse, misuse, and addiction are common when concomitant use of alcohol, illicit substances, or other medication increases the effect of Valium.

So before prescribing Valium, and through treatment, your doctor should assess your risk for abuse, misuse, and addiction.

What are the withdrawal symptoms of Valium?

The use of valium may lead to physical and psychic dependence.

This risk of dependence depends on the dose and duration of treatment and if their history of drug abuse or alcoholism.

So, that is what you feel when stop Valium suddenly:

• Muscle pain.

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